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Research That Shapes the Future of Oncology

Access studies, scientific papers, and published findings advancing cancer diagnostics and care.

ISLB 2024 | Actorius Innovations and Research
25 November 2024
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ISLB 2024: Transit of Circulating Tumor Cells (CTC) Post Radiotherapy at Irradiated Tumor Regions in Pan-cancer Patients

Study links radiotherapy exposure with circulating tumor cells and PD-L1 expression, indicating possible minimal residual disease and metastatic risk.

ISLB 2024 | Actorius Innovations and Research
25 November 2024
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ISLB 2024: Comprehensive Analysis of ctDNA and CTCs Reveals Resistance signatures and Correlations with PET Scan Outcomes in Cancer Patients

Integrated ctDNA and CTC analysis correlates with PET-CT outcomes to reveal treatment resistance and aggressive cancer progression.

ISLB 2024 | Actorius Innovations and Research
25 November 2024
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ISLB 2024: Expression of Programmed Death - Ligand 1 as a dynamic biomarker on circulating tumor cells in pancreatic cancer patients

CTC detection with PD-L1 overexpression reveals aggressive pancreatic cancer and potential biomarker value for monitoring metastasis and disease progression.

ESMO 2024 | Actorius Innovations and Research
17 September 2024
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ESMO 2024: True single-circulating tumor cell genomics reveals enriched therapy-resistance signatures in advanced colorectal cancer patients

Single CTC genomics reveals actionable mutations and therapy resistance signatures not detected in paired ctDNA in advanced colorectal cancer.

ASCO 2024 | Actorius Innovations and Research
4 June 2024
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ASCO 2024: Effect of circulating tumor cells in clinically stable patients on the conundrum of recurrence with cellular residual disease.

CTC detection with PD-L1 expression reveals residual disease despite negative radiological findings in treated cancer patients.

ASCO 2024 | Actorius Innovations and Research
3 June 2024
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ASCO 2024: Effect of circulating tumor cells (CTC) and CTC clusters with PD-L1 dynamic biomarker on cellular burden in patients with ovarian cancer.

CTCs with PD-L1 expression in ovarian cancer reveal minimal residual disease and may guide immunotherapy and early metastasis monitoring.

ASCO 2024 | Actorius Innovations and Research
3 June 2024
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ASCO 2024: Measure of minimal residual burden on CTCs with over-expression of PD-L1 as a dynamic biomarker in patients with colorectal cancer.

CTC detection with PD-L1 expression in colorectal cancer reveals minimal residual disease and supports personalized treatment strategies.

ASCO 2024 | Actorius Innovations and Research
3 June 2024
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ASCO 2024: Impact of ctDNA genomic mutations and CTCs biomarker duo on clinical concordance in localized, progressive, and metastatic disease.

Dual biomarker analysis of ctDNA and circulating tumor cells reveals disease progression and metastasis across multiple cancer types.

ASCO 2024 | Actorius Innovations and Research
3 June 2024
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ASCO 2024: Association of complementing ctDNA and CTCs load on stable and progressive disease in treated patients.

Complementary ctDNA and CTC biomarkers reveal minimal residual disease and predict cancer progression after curative-intent treatment.

AACR 2024 | Actorius Innovations and Research
10 April 2024
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AACR 2024: Distribution prophecy of circulating tumor cell clusters in CTC populace patients of epithelial cancers

Large-scale analysis of circulating tumor cells and clusters reveals their role in predicting aggressive epithelial cancers and treatment resistance.

AACR 2024 | Actorius Innovations and Research
10 April 2024
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AACR 2024: Evaluation of HER-2 expression on circulating tumor cells as a real time biomarker in advanced breast cancer

HER2 analysis on circulating tumor cells using the OncoDiscover® platform enables real-time, non-invasive profiling for improved metastatic breast cancer treatment decisions.

ESMO 2023 | Actorius Innovations and Research
24 October 2023
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ESMO 2023: Expression of PD-L1 and EGFR on circulating tumor cells in advanced Lung cancer patients

CTC analysis using OncoDiscover® enables dynamic detection of PD-L1 and EGFR targets in advanced lung cancer, supporting personalized targeted and immunotherapy decisions.

ASCO 2023 | Actorius Innovations and Research
6 June 2023
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ASCO 2023: Effect of circulating tumor cells distribution in treatment naive and treated patients with advance stage breast cancer on disease burden.

A study of 417 breast cancer patients shows tracking circulating tumor cells (CTCs) effectively monitors therapy response and recurrence risk.

ASCO 2023 | Actorius Innovations and Research
6 June 2023
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ASCO 2023: Circulating tumor cells (CTCs) detection and isolation in different subtypes of early-stage breast cancer patients from Bangladesh.

A trial found CTCs in 60% of early-stage breast cancer patients, notably all HER2-positive cases, linking them to tumor grade. Send the next!

AACR 2023 | Actorius Innovations and Research
19 April 2023
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AACR 2023: Detection of PD-L1, HER2 and EGFR on circulating tumor cells in carcinoma patients.

CTC analysis in 134 patients successfully detected PD-L1, HER2, and EGFR, proving its value as a real-time guide for targeted therapies.

AACR 2023 | Actorius Innovations and Research
15 January 2023
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AACR 2023: Abstract PR007: Comprehensive ctDNA profiling reveals potential metastatic genomic signatures in treatment-naive early-stage breast cancer patients

Comprehensive ctDNA profiling and CTC analysis in early-stage breast cancer identifies driver mutations to predict early metastasis.

ASCO 2022 | Actorius Innovations and Research
7 June 2022
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ASCO 2022: CTCs as a biomarker for monitoring: Disease progression, treatment response, and minimal residual disease.

Study of 127 patients shows CTCs are a dynamic biomarker for monitoring disease progression and therapy response in advanced epithelial cancers.

ASCO. 2022 | Actorius Innovations and Research
7 June 2022
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ASCO 2022: Machine learning (ML)–enabled, circulating tumor cell–based classification of patients for non-prerequisite adjuvant therapy.

An XGBoost ML model using CTCs and clinical data achieved 84% accuracy in predicting the need for adjuvant therapy in 380 HNSCC patients.

ASCO 2022 | Actorius Innovations and Research
7 June 2022
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ASCO 2022: Extracorporeal microchannel device to capture and eliminate circulating tumor cells from
cancer patient’s blood.

A 3D-printed G-EpCAM device successfully captured over 85% of CTCs with minimal hemolysis, offering a new way to stem metastatic progression.

ASCO 2022 | Actorius Innovations and Research
7 June 2022
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ASCO 2022: A feasibility study of EMF (erlotinib+methotrexate+5-fluorouracil) regimen in recurrent HNSCC and role of CTCs in assessment of outcomes.

A phase II trial shows EMF triplet therapy is a safe, effective option for HNSCC, with CTCs serving as a promising biomarker for therapy response.

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