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Research That Shapes the Future of Oncology

Access studies, scientific papers, and published findings advancing cancer diagnostics and care.

Real-Time Therapy Response Monitoring Using Surface Biomarkers on Circulating Tumor Cells
27 January 2026
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Manuscript: Real-Time Therapy Response Monitoring Using Surface Biomarkers on Circulating Tumor Cells

Circulating tumor cells (CTCs), cancer cells shed from primary tumors into the bloodstream, are emerging as dynamic, non-invasive biomarkers for real-time cancer monitoring, especially when tissue biopsies are inaccessible or inadequate...

TSG mutations predict early relapse in mEGFR lung adenocarcinoma.
14 March 2025
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Manuscript: The impact of co-occurring tumor suppressor mutations with mEGFR as early indicators of relapse in lung cancer

A set of 17 co-occurring TSG mutations has been identified as key biomarkers for early relapse in mEGFR
lung adenocarcinoma. Longitudinal genomic monitoring, with a focus on clonal evolution, offers valuable insights that can inform personalized treatment strategies and potentially improve patient outcomes.

Inverse 3D lab-on-chip microfilms for selective CTC capture from blood.
15 July 2024
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Manuscript: Inverse 3D ‘lab-on-a-chip’ polymeric microfilms for selective capture of circulating tumor cells from patients' blood

Inverse 3D lab-on-chip microfilms for selective CTC capture from blood.

CTCs as biomarkers for relapse detection in rectal cancer with liver metastasis.
29 June 2024
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Manuscript: Circulating Tumor Cells as Biomarkers for Relapse Detection in Rectal Cancer with Liver Metastasis: Insights from a Case Report

Nirmal Raut, Atul Bharde, Sreeja Jayant, Gaurishankar Aland, Aravindan Vasudevan, Jayant Khandare

CTC together with Shh and Nrf2 are prospective diagnostic markers for HNSCC
4 April 2024
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Manuscript: CTC together with Shh and Nrf2 are prospective diagnostic markers for HNSCC

Study links Shh/Nrf2 overexpression with circulating tumor cells in HNSCC, highlighting their potential as biomarkers for early detection and survival prediction.

Magnetically activated nanocellulose enables efficient CTC capture in head & neck cancer.
20 September 2023
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Manuscript: Magnetically-activated, nanostructured cellulose for efficient capture of CTCs from the blood sample of head and neck cancer patients

Study compares CNC and CNF cellulose nanostructures for EpCAM-based CTC capture in head and neck cancer, enabling affordable real-time cancer monitoring.

CTCs in recurrent and metastatic head & neck squamous cell carcinoma.
20 July 2023
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Manuscript: Role of circulating tumour cells (CTCs) in recurrent/metastatic head and neck squamous cell carcinoma (HNSCC)

This study highlights the utility of CTCs as a disease progression monitoring tool in recurrent HNSCC patients. Our findings suggest the potential clinical utility of CTCs and the need for further exploration in upfront settings of the disease as well (NCT: CTRL/2020/02/023378).

Chemical tunability of advanced materials used in the fabrication of micro/nanobots
11 April 2023
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Manuscript: Chemical tunability of advanced materials used in the fabrication of micro/nanobots

Review on chemically tunable micro- and nanobots for targeted nanomedicine, highlighting AI materials, applications, and biosafety considerations.

Preoperative CTC levels predict prognosis and survival in oral squamous cell carcinoma.
1 July 2022
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Manuscript: Circulating tumor cells as a predictor for poor prognostic factors and overall survival in treatment nay¨ve oral squamous cell carcinoma patients

Preoperative circulating tumor cell levels strongly correlate with metastasis, disease severity, and reduced survival in oral squamous cell carcinoma patients.

Bioinspired Materials for Wearable Devices and Point-of-Care Testing of Cancer
27 April 2022
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Manuscript: Bioinspired Materials for Wearable Devices and Point-of-Care Testing of Cancer

Raj Shankar Hazra, Md Rakib Hasan Khan, Narendra Kale, Tabassum Tanha, Jayant Khandare, Sabha Ganai, and Mohiuddin Quadir*

Antibody-coated cotton substrate for CTC enumeration and chemotherapy response.
18 February 2022
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Manuscript: Antibody mediated cotton-archetypal substrate for enumeration of circulating tumor cells and chemotherapy outcome in 3D tumors

Cotton microfluidic substrate enables efficient CTC isolation, 3D tumor growth, and drug response testing for improved cancer diagnostics and therapy research.

Chemo-specific designs for the enumeration of CTCs: advances in liquid biopsy
18 December 2020
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Manuscript: Chemo-specific designs for the enumeration of circulating tumor cells: advances in liquid biopsy

Review on chemo-specific nano/micro substrates for efficient CTC isolation, enabling liquid biopsy, metastasis detection, and real-time cancer monitoring.

Cellulose-based transferrin nanocages for CTC enumeration in head & neck cancer.
10 October 2020
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Manuscript: Cellulose Mediated Transferrin Nanocages for Enumeration of Circulating Tumor Cells for Head
and Neck Cancer

Magnetic transferrin-functionalized cellulose nanocages capture circulating tumor cells from blood, enabling liquid biopsy for early metastasis detection in head and neck cancer.

Magnetic nanogels enable optimized capture of circulating tumor cells from blood.
11 February 2018
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Manuscript: Optimizing Circulating Tumor Cells’ Capture Efficiency of Magnetic Nanogels by Transferrin Decoration

Magnetic nanogels with optimized PEG–transferrin linkers achieve over 80% efficiency in selectively capturing circulating tumor cells from blood.

Micropatterned surfaces enable selective cancer cell capture and real-time monitoring.
17 January 2018
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Manuscript: Selective Cell Isolation by Transferrin Functionalized Silane– Carbon Soot Mediated Superhydrophobic Micropatterns

Transferrin-functionalized wettability micropatterns enable selective cancer cell capture and real-time monitoring for diagnostics and recurrence detection.

Biofunctionalized capillary platform with 3D matrix for efficient CTC capture.
17 January 2017
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Manuscript: Biofunctionalized Capillary Flow Channel Platform Integrated with 3D Nanostructured Matrix to Capture Circulating Tumor Cells

Continuous-flow 3D microchannel platform captures circulating tumor cells with ~90% efficiency, enabling liquid biopsy and real-time cancer monitoring.

CaP-crowned CNT nanocapsules enable pH-triggered intracellular anticancer drug delivery.
17 April 2015
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Manuscript:Calcium phosphate nanocapsule crowned multiwalled carbon nanotubes for pH triggered intracellular anticancer drug release

Calcium phosphate–capped carbon nanotubes enable pH-triggered intracellular release of doxorubicin, preventing premature drug leakage and improving targeted cancer therapy.

Self-propelled CNT microrockets enable rapid capture and isolation of CTCs.
13 April 2015
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Manuscript: Self-propelled Carbon Nanotube Based Microrockets for Rapid Capture and Isolation of Circulating Tumor Cells

Self-propelled CNT microrockets rapidly capture and magnetically isolate circulating tumor cells, enabling faster liquid biopsy and early cancer detection.

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